actifedActifed is a registered trademark for a combination antihistamine and nasal decongestant medication used for cold and allergy symptoms. Developed in 1958 by Burroughs Wellcome & Company (now part ofGlaxoSmithKline), the product was later acquired by Pfizer, and was most recently sold by Johnson & Johnson. In the U.S., the formula was changed in 2006 due to a change in the legal environment; at the same time, distribution of the product was limited to certain stores.

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